Fragile begins in Hollows, a quaint little town near New York City where everybody knows everybody. Or do they? When Charlene, a young local teen goes missing, her disappearance strikes uncomfortably close to home for psychiatrist Maggie and Jones, her policeman husband.

Twenty years ago, when they and Charlene’s mother, Melody, were in high school, Maggie’s best friend, Sarah, was found brutally murdered. Jones and Melody carry a secret from that time–one that involves another former classmate, school bully turned cop, Travis. Now both Maggie and Jones’ son Ricky and Travis’ son, Marshall, are prime suspects in Charlene’s disappearance.